Amelie G. Ramirez • Edward J. Trapido Editors 2023 Building Collaboration for Action The Advancing the Science of Cancer in Latinos national conference was a call to action for addressing cancer health disparities in Hispanic/Latino communities. It emerged from the need for Latino disparities researchers to seek solutions through multidisciplinary collaborations and to keep pace […]

Edited by Anton W. Langerak 2022 Adaptive immune cells (lymphocytes) are equipped with unique antigen receptors, termed immunoglobulins (IG) and T cell receptors (TR), which collectively form a highly diverse repertoire. In the lymphocytes, IG/TR diversity is actually created at the DNA level, thus giving rise to an enormous adaptive immune receptor repertoire (also known […]

Edited by Karl-Dieter Entian 2022 Ribosomes are the organelles that synthesize proteins according to the genetically encoded information. Whereas prokaryotic ribosomes were even reconstituted in vitro, eukaryotic ribosomes are more complex. In yeast—as a eukaryotic model organism—about 5–10% of the genomic capacity is needed for the biogenesis of a ribosome. Worldwide a remarkable number of […]

Editor Anne Le 2021 Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic fexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism […]

Anton Bespalov • Martin C. Michel • Thomas Steckler Editors 2020 Pharmacologists and other experimental life scientists study samples to infer conclusions about how a molecule, cell, organ, and/or organism work in health and disease and how this can be altered by drugs. The concept of inference implies that whatever is reported based on the […]

Kota Miura Nataša Sladoje Editors 2020 The often-posed question among life science researchers, “Which software tool is the best for bioimage analysis,” indicates misunderstanding which calls for explanations. It appears that this question cannot be answered easily, maybe even not at all. Biological research problems are not general, and each of them questions specific events […]

Francisco M. Couto 2019 During the last decades, I witnessed the growing importance of computer science skills for career advancement in Health and Life Sciences. However, not everyone has the skill, inclination, or time to learn computer programming. The learning process is usually time consuming and requires constant practice, since software frameworks and programming languages […]

Gerd Pluschke • Katharina Röltgen Editors 2019 Mycobacterium Ulcerans Disease Within the 20 years after WHO has launched the Global Buruli Ulcer Initiative in 1998, considerable progress has been made toward the understanding and the control of this neglected, once mysterious, tropical skin disease. Major practical achievements were the evaluation and successful introduction of an antibiotic […]

Bruce Spiegelman Editor 2017 We gathered in Paris to present new work on exercise and the molecular understanding of its actions and benefits. Exercise has been understood for centuries to provide benefits to the human body. Diet and exercise have long been prescribed as the first lines of therapy for metabolic diseases such as obesity and […]

Mitchell Fry 2010 To the uninitiated, biochemistry is a complex and intricate subject, but importantly it is a subject that underpins the biosciences, including medicine. As a university lecturer, and by training a biochemist, I have taught my subject to both ‘my own’ students, and to those on allied degree schemes and pre-clinical medicine. Of course, the lines […]