Mitchell Fry 2010 To the uninitiated, biochemistry is a complex and intricate subject, but importantly it is a subject that underpins the biosciences, including medicine. As a university lecturer, and by training a biochemist, I have taught my subject to both ‘my own’ students, and to those on allied degree schemes and pre-clinical medicine. Of course, the lines […]

Edited by Stefan Pöhlmann Graham Simmons 2013 For a virus to invade a host cell it needs to penetrate the physical barrier imposed by the plasma membrane. Viruses have evolved specialized surface proteins to meet this challenge. These proteins facilitate delivery of the viral genetic information into the host cell by either fusing the viral envelope with a […]

Yuichi Sugiyama • Bente Steffansen Editors 2013 Discovery, Optimization, Clinical Study and Regulation This volume of AAPS Advances in Pharmaceutical Sciences Series presents a review of the principles and progress concerning membrane transporters and how evolved understanding of membrane transporters has influenced drug development and regulatory assessment. The objective of the book is to present current knowledge in […]

Gary Hime • Helen Abud Editors 2013

Tulasi Satyanarayana • Jennifer Littlechild Yutaka Kawarabayasi Editors 2013 Biotechnology of Thermophiles It is now very well known that microbial life can thrive in the upper as well as lower temperature limits that are known to be compatible with life. Temperature provides a series of challenges, from structural devastation due to ice crystal formation at one extreme to […]

Moshe Oren ● Yael Aylon Editors 2013

Richard Brooks 2013 When a small group of people from differing professional backgrounds and disciplines met in 1987 with the common aim of developing a health-related quality of life instrument that would suit their requirements it is doubtful if any of the participants expected that the resulting instrument would have the global reach it has today. This book shows […]

Alberto J. L. Macario Everly Conway de Macario Francesco Cappello 2013 Diseases with Defective Molecular Chaperones This book is about a number of pathological conditions, the chaperonopathies, which probably existed since remote times and have been studied for years but were grouped together in a coherent nosological category only recently. The book is intended to be an introduction […]

John Geigert 2013 Preparing the 2nd edition of my book was a humbling experience for me. My primary purpose for updating the 1st edition was to continue to provide relevant insight and practical suggestions for a risk-managed, common sense, scientific, practical business approach to managing the Chemistry, Manufacturing and Controls (CMC) regulatory compliance requirements and expectations for biopharmaceuticals as human […]