Edited by
Anton W. Langerak

2022

Adaptive immune cells (lymphocytes) are equipped with unique antigen receptors, termed immunoglobulins (IG) and T cell receptors (TR), which collectively form a highly diverse repertoire. In the lymphocytes, IG/TR diversity is actually created at the DNA level, thus giving rise to an enormous adaptive immune receptor repertoire (also known as the immunome) that can be studied in healthy and diseased subjects in the context of research questions and clinical applications. This field of (fundamental and translational) research is known as immunogenetics.