Peter C. Ruben
Editor

2014

Just over 60 years ago, Hodgkin and Huxley first proposed the ionic basis of the action potential in neurons. Their insightful—and foresighted—work, based on experiments performed in squid giant axons, laid the groundwork for a new research field: ion channel biophysics. The elegance and importance of their work earned them a Nobel Prize 11 years after their groundbreaking work was first published and set the stage for other ion channel biophysicists to follow in their footsteps: Sakmann and Neher (1991) and MacKinnon (2003).