The Role of Microbes in Common Non-Infectious Diseases

The Role of Microbes in Common Non-Infectious Diseases-1

I.W. Fong 2014 Our understanding of the pathogenesis and etiology of new and venerable diseases has progressed tremendously in the past 30 years, due to improved technology and advances in genomics and molecular science. However, there are several common diseases where the exact causation still eludes investigators, but intensive research over the past decade has provided clues […]

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Human Fungal Pathogens

Human Fungal Pathogens

Edited by K. Esser 2014 The Mycota A Comprehensive Treatise on Fungi as Experimental Systems for Basic and Applied Research XII Volume Books are old-fashioned. Books are never up-to-date, expensive and impractical. And books don’t pay off for those who spend time and effort writing them. All these thoughts are among the first reactions evoked when contacting […]

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Sphingosine-1-Phosphate Signaling in Immunology and Infectious Diseases

Sphingosine-1-Phosphate Signaling in Immunology and Infectious Diseases-1

Michael B. A. Oldstone • Hugh Rosen Editors 2014 For convenience, the early immune response occurring during the first few days after exposure to a foreign agent is termed innate, while the later response, after day 5, is termed adoptive. Both immune responses have defined cellular components although they vary according to different types of cells and the […]

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Liver Immunology

Liver Immunology-1

M. Eric Gershwin • John M. Vierling Michael P. Manns Editors 2014 Principles and Practice Recognition of the importance of the liver to health by Babylonians in the nineteenth century BCE stands in stark contrast to the relative obscurity of the liver in the minds of most educated adults today. Medical appreciation of the vital nature of […]

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Immunology of Aging

Immunology of Aging-1

Ahmad Massoud • Nima Rezaei Editors 2014 Aging is defined as the accumulation of changes in a person over time. It is well established that the overall immune function declines with advancing age, a phenomenon referred to as immunosenescence. Several studies have been performed during recent decades, indicating the pathological consequences of age-related changes in the immune system, leading […]

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IgG4-Related Disease

IgG4-Related Disease-1

Hisanori Umehara • Kazuichi Okazaki John H. Stone • Shigeyuki Kawa Mitsuhiro Kawano Editors 2014 The past decade has witnessed the birth of a “new” multi-organ system, immune-mediated disease now known by consensus as IgG4-related disease (IgG4-RD). Excitement about this disease has stemmed both from the recognition of aspects of the disease that are truly new and from […]

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How Helminths Alter Immunity to Infection

How Helminths Alter Immunity to Infection-1

William Horsnell Editor 2014 Helminth infections occur globally and all individuals are at some point in their life likely to be exposed to these parasites. Humans have always hosted parasitic worm infections and there is clear evidence that number of important helminth parasites have co-evolved with us. As such helminth infections should be considered a metazoan faunal complement to […]

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Drugs Targeting B-Cells in Autoimmune Diseases

Drugs Targeting B-Cells in Autoimmune Diseases-1

Xavier Bosch • Manuel Ramos-Casals • Munther A. Khamashta Editors 2014 Systemic autoimmune diseases are complex multisystemic illnesses whose management may involve any specialty, although the most closely involved physicians are normally rheumatologists and internists. The majority of systemic autoimmune diseases, such as rheumatoid arthritis, systemic lupus erythematosus, progressive systemic sclerosis, primary Sjo¨gren syndrome, inflammatory myopathies, and ANCA-associated vasculitis, have […]

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