Hisanori Umehara • Kazuichi Okazaki
John H. Stone • Shigeyuki Kawa
Mitsuhiro Kawano
Editors

2014

The past decade has witnessed the birth of a “new” multi-organ system, immune-mediated disease now known by consensus as IgG4-related disease (IgG4-RD). Excitement about this disease has stemmed both from the recognition of aspects of the disease that are truly new and from understanding certain features recognized in previous eras in a novel, broader context. IgG4-RD can be tracked readily back through every decade of the last century and easily into the 1800s, but there is little reason to believe that the condition is not far older.