Ahmad Massoud • Nima Rezaei
Editors

2014

Aging is defined as the accumulation of changes in a person over time. It is well established that the overall immune function declines with advancing age, a phenomenon referred to as immunosenescence. Several studies have been performed during recent decades, indicating the pathological consequences of age-related changes in the immune system, leading to a variety of manifestations such as increased susceptibility to infections and an increased tendency toward autoimmunity and immunopathology. Immune function in elderly is not deteriorating by random; rather, it appears to be under genetic control, as well as environmental factors such as diet and lifestyle.