Functional Selectivity of G Protein-Coupled Receptor Ligands
Edited by Kim A. Neve 2009 New Opportunities for Drug Discovery Functional selectivity refers to the observation that different ligands acting at one subtype of receptor that couples to multiple signaling pathways can vary in their ability to activate the signaling pathways; that is, one drug can be an agonist at pathway A and an antagonist or partial […]
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