Edited by VICTOR M. MONTORI 2006 This book is about evidence-based endocrinology, but it is not a “how-to-do-it” evidence-based medicine manual (indeed several other books are available that fulfill this objective optimally). It is a broad-ranging collection of essays, each with its own voice, that place evidence-based medicine in the context of endocrine practice and policy. My instruction to […]
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Edited by G. Molineux, M.A. Foote, and S.G. Elliott 2006 Molecular, Cellular, Preclinical, and Clinical Biology Research on, and interest in, red blood cell formation spans several centuries and was thought to have peaked in the 1980s with the cloning of the erythropoietin (EPO) gene. In the years subsequent to the cloning of EPO and its expression as […]
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Edited by Chen Hsing Hsu 2006 The kidney is one of the most complex organs. Once it fails, it can no longer carry out the complicated tasks performed by the normal kidney. The ensuing disorders of calcium (Ca) and phosphate (P) metabolism are common and difficult problems in chronic kidney disease (CKD). This book is intended for medical students, […]
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Edited by Ora H. Pescovitz Emily C. Walvoord 2007 Scientific and Clinical Aspects When puberty is precocious is a question in and of itself. The possibility that puberty is starting earlier in children of the 21st century has become a contentious topic during the past few years.
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Edited by ROBERT F. KUSHNER DANIEL H. BESSESEN 2007 The rising prevalence of obesity among children and adults is one of the most significant threats to our nation’s health as we enter the 21st century. Among a host of disorders associated with obesity that affect multiple organ systems, the escalating prevalence of type 2 diabetes and conditions associated […]
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Edited by ANITA H. PAYNE MATTHEW P. HARDY 2007 Ten years ago, in association with Lonnie Russell, we published The Leydig Cell (Cache River Press, Vienna IL). It was the first volume of its kind, devoted entirely to review chapters covering basic and clinical aspects of Leydig cell structure and function.
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Edited by Alexander I. Agoulnik 2007 When Dr. Aaron Hsueh and his colleagues reported the discovery of the relaxin receptors in Science in 2002, the editorial written by Dr. Richard Ivell was entitled “This hormone has been relaxin’ too long!” Indeed, despite the fact that relaxin was the first peptide hormone discovered more than 80 years ago in […]
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Alan R. Saltiel Jeffrey E. Pessin 2007 We now know that the pathophysiology of Type 2 diabetes involves defects in three organ systems that conspire together to produce abnormal glucose and lipid metabolism. While there is some uncertainty regarding the primary lesion, or relative importance of different tissues, metabolic defects in liver, peripheral target tissues such as fat and muscle […]
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Edited by V. Daniel Castracane Michael C. Henson 2007 The discovery of leptin by Friedman and his colleagues in 1994 was a seminal discovery in the study of metabolism, providing a new tool to study energy expenditure and appetite regulation. Early studies actively investigated many aspects of metabolism, obesity, and diabetes but it was soon evident that leptin was […]
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Edited by ROBERT M. CAREY 2007 Hypertension, a major risk factor for cardiovascular disease and stroke, is present in approximately one-quarter of the adult population of Western societies. Seven percent of deaths worldwide are attributed to hypertension, and the rate of end-stage renal disease due to hypertension has doubled since 1982.
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