Immunogenetics: Methods and Protocols

Immunogenetics-1

Edited by Anton W. Langerak 2022 Adaptive immune cells (lymphocytes) are equipped with unique antigen receptors, termed immunoglobulins (IG) and T cell receptors (TR), which collectively form a highly diverse repertoire. In the lymphocytes, IG/TR diversity is actually created at the DNA level, thus giving rise to an enormous adaptive immune receptor repertoire (also known […]

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Ribosome Biogenesis: Methods and Protocols

Ribosome Biogenesis-1

Edited by Karl-Dieter Entian 2022 Ribosomes are the organelles that synthesize proteins according to the genetically encoded information. Whereas prokaryotic ribosomes were even reconstituted in vitro, eukaryotic ribosomes are more complex. In yeast—as a eukaryotic model organism—about 5–10% of the genomic capacity is needed for the biogenesis of a ribosome. Worldwide a remarkable number of […]

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Global guidance on criteria and processes for validation: elimination of mother-to-child transmission of HIV, syphilis and hepatitis B virus

Global guidance on criteria and processes for validation-1

World Health Organization 2021 The global community has committed to eliminating mother-to-child transmission (EMTCT), also known as vertical transmission, of HIV and syphilis as a public health priority. In 2014 the World Health Organization (WHO) released the first edition of the Global guidance on criteria and processes for validation: elimination of mother-to-child transmission of HIV […]

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