Peter F. Buckley • Fiona Gaughran
Editors

2014

A Clinical Conundrum

It is a far too frequent occurrence that patients with schizophrenia don’t respond adequately or return to function using current pharmacological and nonpharmacological treatment approaches. As schizophrenia is fundamentally characterized by recurrent relapses, the extent to which a refractory treatment status represents a de novo, more severe form of psychosis or occurs in evolution over the course of a deteriorative illness is a fundamental consideration.