Adam R. Karpf
Editor
2013
Epigenetics refers to heritable changes in gene expression or genome function encoded by marks other than DNA base sequence; information literally “above” the level of genetics. Epigenetic marks include cytosine methylation and cytosine hydroxymethylation, histone tail modi fi cations, histone variants, and nucleosome positional information, all of which are resident along the DNA duplex. Epigenetic marks frequently show interdependent relationships, for example, the close association of DNA methylation states with particular histone tail modi fi cations and histone variants.