Hernani D. Cualing • Marshall E. Kadin
Mai P. Hoang • Michael B. Morgan
Editors

2014

Approach to the Diagnosis of
Atypical Lymphoid-Hematopoietic
Infi ltrates in Skin

The difficulty in diagnosis of cutaneous atypical lymphoid infiltrate is well known to both hematopathologists and dermatologists. Hence, it is not uncommon to have multiple biopsies to arrive at a diagnosis of cutaneous lymphoma. Part of the difficulty is the wide clinical and pathological overlap between reactive and malignant lymphoid infiltrate in the skin. The other reason may be the lack of a framework to classify these lesions, which may also be related to the fact that a select few hematopathologists and dermatopathologists specialize in these relativelyrare, difficult to diagnose and confusing disease.