Philip Rubin • Louis S. Constine
Lawrence B. Marks
Editors

2014

Volume 2: Normal Tissue Specific Sites
and Systems

The publication in 1968 of the book by Rubin and Casarett entitled Clinical Radiation Pathology, in Volumes I and II, represented a hallmark statement regarding the late effects related to radiation therapy. The new text by Rubin and his co-workers comprehensively documents contemporary understanding of the adverse late effects of cancer treatment in a coherent, multidisciplinary approach related to the care of cancer survivors. All major organs are affected by the treatment program, whether it be radiation, chemotherapy, or surgical treatment, and these impacts must be taken into consideration in any discussion on what might be the most appropriate treatment in cancer management. Modern cancer treatment is clearly based on safe intensification of radiation therapy, chemotherapy, and biologic modifiers.