Function and Control of the Spx-Family of Proteins Within the Bacterial Stress Response

Function and Control of the Spx-Family of Proteins Within the Bacterial Stress Response-1
Peter Zuber
2013
A complex regulatory network governs the microbial response to encounters with harsh environmental conditions. Such networks also influence essential decisionmaking processes that coordinate metabolic pathways and maintain cellular ultrastructure. The study of such networks has been a fruitful area of research over the years, and continues to be a major focus of biomedical, applied, and environmental studies. Investigations using model bacterial systems revealed conserved mechanisms that neutralize harmful conditions by destroying toxic agents or alleviating their damaging effects. Molecular genetic studies of the model enteric bacterium,
Escherichia coli, uncovered complex signal transduction, and response systems that govern the processes of toxicity/damage control…

 

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