Coronary Microvascular Dysfunction

Coronary Microvascular Dysfunction-1

Filippo Crea • Gaetano A. Lanza
Paolo G. Camici

2014

Obstructive disease of the epicardial coronary arteries has been accepted as the cause of angina pectoris for more than two centuries, and sudden thrombotic occlusion of an epicardial coronary artery has been well established as the cause of acute myocardial infarction for more than one hundred years. Therefore, attention has focused on these vessels from both a diagnostic and therapeutic viewpoint. In 1958 Sones introduced coronary arteriography, which provided a ‘‘road map’’ of the epicardial coronary arterial tree.

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