Philip J. Cowen
Trevor Sharp
Jennifer Y. F. Lau Editors

2013

Current Topics in Behavioral Neurosciences
Volume 14

Major depressive disorder (MDD) is remarkably common. At any one time, worldwide, over 120 million people may be suffering from depression. Lifetime risks vary from 10 to 25 % for women and 5 to 12 % for men for Major Depression, with some indication that these estimates have risen over the past two decades. MDD is defined by episodes of low mood and/or anhedonia with changes in physical and psychological function. These episodes are highly recurrent.