World Health Organization

2021

Thalassaemias are the most common monogenetic inherited disorders of haemoglobin (Hb). The inheritance of thalassaemias is autosomal recessive. Thalassaemias are globally prevalent, although prevalence varies widely between countries of the same region, and even within countries. Originally restricted to specific geographical locations, thalassaemias are now global due to population migration. α- thalassaemia is more frequent in the WHO South-East Asia Region than in other parts of the world.