Jonathan Mamou • Michael L. Oelze
Editors

2013

In the 1970s, Holasek, Gans, Purnell, and Sokollu expressed the notion that the frequency content of medical-ultrasound echo signals might be exploited to characterize soft tissue; they developed a method of color-encoding of B-scan images to depict spectral content of RF echo signals and termed the method ‘‘spectra color.’’ By characterize, they essentially meant to distinguish one type of soft tissue from another, for example, to distinguish a cancerous lesion from a benign one, to track changes in tissue over time, or to monitor the progression or regression of disease.