Molecular Biology of Long Non-coding RNAs

Molecular Biology of Long Non-coding RNAs-1

Ahmad M. Khalil • Jeff Coller
Editors

2013

The mammalian genome encodes both coding and non-coding transcripts that work synergistically to build and organize cellular structures, and regulate gene expression patterns, which ultimately determine cell identity and function. While coding transcripts serve mostly as templates for protein synthesis, non-coding RNA transcripts, which by definition lack significant protein-coding capacity, participate in a wide range of cellular functions.

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