Edited by
Michael Balls
Robert D. Combes
Nirmala Bhogal

2012

The central theme running through this volume on New Technologies for Toxicity Testing is the development and application of advanced techniques for cell and tissue culture, as well as new markers and endpoints of toxicity, as alternatives to the traditional paradigm of relying on data from laboratory animal tests to undertake labelling and risk assessment. Many such in vivo tests have been shown to be based on outdated and imprecise methodologies and experimental designs, and the large majority have never been subjected to formal validation to establish their reliability and relevance.