Constantinos Koumenis • Ester Hammond
Amato Giaccia
Editors

2014

Signaling, Metabolism, Imaging,
and Therapeutic Targets

The tumor microenvironment has long been recognized for the critical roles it plays in both promoting the malignant progression of solid tumors and modifying the response of solid tumor cells to cytotoxic or targeted therapy. This book comprises 12 chapters that provide critical insights into how changes in the tumor microenvironment affect tumor metabolism, cell stemness, cell viability, genomic instability, immune modulation, and metastasis.