A Systems Biology Approach to Study Metabolic Syndrome

A Systems Biology Approach to Study Metabolic Syndrome-1

Matej Orešic • Antonio Vidal-Puig


The prevalence of the Metabolic Syndrome (MetS), an entity defined as the coincidence in the same individual of obesity, insulin resistance, dyslipidemia, hypertension and increased cardiovascular morbidity is increasing with a profile that could be considered of epidemic proportions. It is clear that on top of its undeniable genetic contribution other environmental factors such as lack of physical activity, diet, gut microflora and/or ageing are likely contributors to its progressive acceleration.

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