Fundamentals of Clinical Trials

Fundamentals of Clinical Trials-1

Lawrence M. Friedman • Curt D. Furberg
David L. DeMets • David M. Reboussin
Christopher B. Granger


The clinical trial is “the most definitive tool for evaluation of the applicability of clinical research.” It represents “a key research activity with the potential to improve the quality of health care and control costs through careful comparison of alternative treatments”. It has been called on many occasions, “the gold standard” against which all other clinical research is measured.


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