Edited by
Jasjit S. Suri
David L. Wilson
Swamy Laxminarayan
2005
In Chapter 1 we present in detail a framework for fully automated brain tissue classification. The framework consists of a sequence of fully automated state of the art image registration (both rigid and nonrigid) and image segmentation algorithms. Models of the spatial distribution of brain tissues are combined with models of expected tissue intensities, including correction of MR bias fields and estimation of partial voluming.