Edited by
Haruo Sugi

2005

Fifty Years of Research

Fifty years have passed since the monumental discovery that muscle contraction results from relative sliding between the thick filaments, consisting mainly of myosin, and the thin filaments, consisting mainly of actin (A.F. Huxley and Niedergerke, Nature 173; 971-973, 1954; H.E, Huxley and Hanson, Nature 173: 973-976, 1954). Until the early 1970′s, considerable progress have been achieved in the research field of muscle contraction.