Anver Kuliev
2013
Second Edition
The casual reader may not fully appreciate the signifi cance of the well-chosen title for this unique and welcome second edition of Practical Preimplantation Genetic Diagnosis . The title is not only apropos but provided by the team that truly made it possible. Prenatal genetic diagnosis began in the 1950s, with detection of X-chromatin in amniotic fl uid cells. By the late 1960s amniocentesis allowed diagnosis of chromosomal abnormalities and selected inborn errors of metabolism. Prenatal genetic laboratories sprang up worldwide, and by the 1970s antenatal testing became standard for certain patients.