Christopher G. Janson
Matthew J. During

2006

When this book project was first contemplated, some of the molecules and applications discussed in this volume (such as mammalian siRNA) did not yet exist, which speaks to the relative progress in the antisense field and the likelihood that fiirther chemical modifications of existing classes of molecules will lead to even more enhanced and greater use of “gene tools” in the future. The original intention of the publisher was to devote an entire book to Peptide Nucleic Acid (PNA), which was an incipient but fast-growing field.