Guillermo Ortiz-Ruiz
Marco A. Perafán
Eugen Faist
Carmelo Dueñas Castell
Editors

2006

The mortality of severe sepsis (infection-induced organ dysfunction or hypoperfusion abnormalities) and septic shock (hypotension not reversed with fluid resuscitation and associated with organ dysfunction or hypoperfusion abnormalities) remains unacceptably high. Similar to an acute myocardial ischemic attack and an acute brain attack, the speed and appropriateness of therapy administered in the initial hours after the syndrome develops likely influence the outcome.