Ursula Jakob • Dana Reichmann
Editors

2013

Reactive oxygen species (ROS) have long been branded as undesired cytotoxic compounds to be avoided at all costs. This view has changedwith the realization that ROS, which are constantly produced in all aerobic organisms, play essential roles in a plethora of signaling processes that act to control cell differentiation, proliferation, and apoptosis. It is now clear that organisms need to achieve a fine-tuned balance between oxidants and antioxidants (i.e., redox homeostasis) in order to function properly.At the heart of many cellular ROS-controlled processes are redox-sensitive proteins.