Editor
Mikhail V. Kiselevsky

2008

Traditional understanding of anti-tumor immunity is based on the theory of immunological surveillance and it suggests function of cytotoxic lymphocytes that can recognize tumor-specific antigens and lyse malignantly transformed cells. However tumor development is not the direct result of immune system disorders and even in case of marked immuno-deficiencies, in particular, in patients – transplant recipients, immune dysfunction does not always lead to higher cancer incidence comparing with total population.