Drug Product Development for the Back of the Eye

Drug Product Development for the Back of the Eye-1

Uday B. Kompella • Henry F. Edelhauser
Editors

2011

Age-related macular degeneration and macular edema are major vision-threatening disorders of the back of the eye. The first therapeutic agents for treating these diseases, Macugen™ (Pfizer, a nucleic acid-based drug), Lucentis™ (Genentech; a protein drug), and Ozurdex™ (Allergan; a small molecule drug in a biodegradable, injectable implant) were approved by the US FDA in 2004, 2006, and 2009, respectively.

 

 

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