Fan Lin • Jeffrey Prichard
Editors

2011

Over the past 20 years, four key discoveries can be viewed as the cornerstones in the continuing evolution of immunohistochemistry (IHC). They include (1) the development of monoclonal antibodies, significantly increasing diagnostic specificity; (2) the introduction of heat-induced and proteolytic enzyme antigen retrieval methods, providing a foundation for the utility of IHC on formalin-fixed paraffin-embedded surgical specimens….