Caio Maximino

2012

Neuroanatomical, Pharmacological,
and Functional Aspects

Along with benzodiazepines, drugs targeting the serotonergic system represent the major class of anxiolytic drugs. Among available serotonergic drugs, selective serotonin reuptake inhibitors still represent the most prescribed treatment for anxiety disorders, even though they are associated with low efficacy in a considerable proportion of patients, a delayed onset of therapeutic action, and diverse collateral effects which reduce tolerance (e.g., sexual dysfunction, weight changes).