JIMD Reports Volume 16
Johannes Zschocke • K. Michael Gibson Editors-in-Chief Garry Brown • Eva Morava Editors Verena Peters Managing Editor 2014
Continue reading →Category: Human Genetics
JIMD Reports Volume 12
Johannes Zschocke • K. Michael Gibson Editors-in-Chief Garry Brown • Eva Morava Editors Verena Peters Managing Editor 2014
Continue reading →JIMD Reports Volume 13
Johannes Zschocke • K. Michael Gibson Editors-in-Chief Garry Brown • Eva Morava Editors Verena Peters Managing Editor 2014
Continue reading →Impact of Sleep and Sleep Disturbances on Obesity and Cancer
Susan Redline • Nathan A. Berger Editors 2014 Sleep has recently been recognized as a critical determinant of energy balance, regulating restoration and repair of many of the physiological and psychological processes involved in modulating energy intake and utilization. Emerging data indicate that sleep can now be added to caloric intake and physical activity as major determinants of energy […]
Continue reading →I Domain Integrins
Donald Gullberg Editor 2014 The integrin family is composed of 24 members [5]. Ten years ago we published a book devoted to the nine aI domain integrin subunits [24]. These are shown in Fig. 1. I am pleased that most of the original authors have been able to contribute to the updated version. In 2003, the knockout mouse phenotypes […]
Continue reading →Hormones, Intrauterine Health and Programming
Jonathan R Seckl • Yves Christen Editors 2014 In the last two decades a plethora of studies have extended the classical genes adult environment paradigm of disease aetiology to include early life development (genes development environment). An early and powerful example comes from the epidemiological studies of Barker and colleagues linking low birth weight (a rather […]
Continue reading →Genetic Damage in Human Spermatozoa
Elisabetta Baldi • Monica Muratori Editors 2014 The goal of male gametes is to deliver a fully intact and functioning paternal genome to the oocyte. To fulfill this aim, the process of chromatin maturation during spermiogenesis must be correctly completed to guarantee DNA protection during the long journey to reach the oocyte and to properly decondense and form […]
Continue reading →Epigenetic Therapy of Cancer
Michael Lübbert • Peter A. Jones Editors 2014 Preclinical Models and Treatment Approaches The view that cancer is primarily a genetic disease has been dramatically challenged by the recent discoveries demonstrating that malignancies are marked by multiple epigenetic abnormalities; the resultant gene silencing may be more ubiquitous than gene inactivation by genetic events. This paradigm change was accompanied […]
Continue reading →Regenerative Medicine for the Inner Ear
Juichi Ito Editor 2014 Inner ear diseases such as sensorineural hearing loss (SNHL), tinnitus, and dizziness are very difficult to treat, especially in cases with highly severe hearing disturbance. While the use of cochlear implants in profoundly deaf patients has been encouragingly useful, further improvement in the efficacy of this device is desirable. Recently, regenerative medicine has made great […]
Continue reading →Advances in Nutrition and Cancer
Vincenzo Zappia • Salvatore Panico Gian Luigi Russo • Alfredo Budillon Fulvio Della Ragione Editors 2014 This volume includes 26 contributions presented at the Third International Conference on Advances in Nutrition and Cancer held in Naples, Italy, in May 2012 at the National Institute for Cancer Research. The major aim of the meeting was to illustrate the most […]
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