Robert Yarchoan Editor 2014 Progress and Challenges The field of HIV-associated cancer has undergone a number of changes and advances in the past several years, and this book was conceived to fill the need for a resource that summarizes this new information. The 28 chapters describe the current state of knowledge in this area. These chapters were written […]
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Lorenzo Emmi Editor 2014 From Pathogenesis to Treatment About 30 years ago, I started to be in confidence with Behçet syndrome; at that time only a few lines in all the major texts of Internal Medicine were dedicated to this entity, not only in Italy. As I look back to those times when Dr. Ignazio Olivieri and some […]
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Dane Parker Editor 2014 Type I interferon (IFN) signaling has long been recognized as a critical component of innate immune defense to viral pathogens. It is now established that bacteria too are able to activate this pathway. Typically bacteria activate type I IFN signaling through TLR-dependent mechanisms, through recognition of LPS in Gram negative organisms or via TLRs and […]
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Hubert Hilbi Editor 2013 Legionnaires’ disease is a potentially fatal pneumonia primarily affecting elderly and immunocompromised persons. The disease is caused by the ubiquitous environmental bacterium Legionella pneumophila, which was first identified more than 35 years ago in the aftermath of a pneumonia epidemic that swept through a convent of the American Legion in Philadelphia, USA. The water-borne bacteria are […]
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William J. Meggs Editor 2013
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Fedor Berditchevski • Eric Rubinstein Editors 2013 Since arriving at the molecular scene more than 20 years ago tetraspanins continue to capture imagination of researchers in various fi elds of biology. Initially described as targets for tumour-speci fi c mAbs (CO-029/TSPAN8, ME491/CD63), the antiproliferative mAb (TAPA-1/CD81/TSPAN28), and the antibodies recognising “cluster differentiation” (CD) antigens (CD9/TSPAN29, CD37/TSPAN26 and CD53/TSPAN25), tetraspanins later […]
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Thomas J. Rogers • Gerard J. Criner William D. Cornwell Editors 2013 Basic, Pre-Clinical and Clinical Research Advances It is clear that chronic obstructive pulmonary disease (COPD) is a chronic infl ammatory disease state which is the result of multiple insults to the lung, and the resulting infl ammatory response is highly complex. Studies over the last 25 […]
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Sabine Van Huffel • Gunnar Naulaers Alexander Caicedo • Duane F. Bruley David K. Harrison Editors 2013 The 40th Annual Meeting of the International Society on Oxygen Transport to Tissue (ISOTT ) was held on August 19–24, 2012, at the Novotel hotel in Bruges, Belgium. The historic city of Bruges, called “The Venice of the North,” provided […]
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William J. Welch Fredrik Palm Duane F. Bruley David K. Harrison Editors 2013 The 39th annual ISOTT conference was held on the campus of Georgetown University in the capital of the USA. The urban campus of the Jesuit institution provided an ideal setting for the exchange of ideas and research from this organization. The program covered many […]
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T. Metin Önerci Editor 2013 The human nose protruding as a pyramid from the midface is unique in the realm of mammals. In the earlier days, the nose was considered as an important structure in the middle of the face aesthetically and as a simple double tube for the passage of air to the lungs. It was also […]
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