Placebo

Placebo-1

Fabrizio Benedetti • Paul Enck • Elisa Frisaldi • Manfred Schedlowski Editors 2014 A recent meeting on placebo and nocebo responses, sponsored by the Volkswagen Foundation, and held in Tuebingen (Germany) in January 2013, represented the starting point for inviting many scientists involved in experimental placebo and nocebo research to contribute to this volume by […]

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Behavioral Neurobiology of Chronic Pain

Behavioral Neurobiology of Chronic Pain-1

Bradley K. Taylor • David P. Finn Editors 2014 Current Topics in Behavioral Neurosciences Volume 20 The physiological pain in humans that initially results from tissue injury is an unpleasant and aversive experience with sensory, cognitive, and motivational components. These interact to precipitate behavioral and psychological responses that serve essential survival functions, including protective behaviors […]

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Pediatric Formulations

Pediatric Formulations-1

Daniel Bar-Shalom • Klaus Rose Editors 2014 A Roadmap This is the first book of its kind that specifically addresses pediatric formulations in the context of drug development. Before you read it, we hope that you have asked yourself why such a book was not published 50 or 100 years earlier. When we were asked […]

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Voltage Gated Sodium Channels

Voltage Gated Sodium Channels-1

Peter C. Ruben Editor 2014 Just over 60 years ago, Hodgkin and Huxley first proposed the ionic basis of the action potential in neurons. Their insightful—and foresighted—work, based on experiments performed in squid giant axons, laid the groundwork for a new research field: ion channel biophysics. The elegance and importance of their work earned them […]

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Pharmacological Treatment of Acute Coronary Syndromes

Pharmacological Treatment of Acute Coronary Syndromes-1

Pablo Avanzas • Peter Clemmensen Editors 2014 Acute coronary syndromes (ACS) require rapid intervention with pharmacologic therapies to treat and prevent coronary thromboembolism, and is essential to prepare the patient for revascularization procedures, especially percutaneous coronary intervention. The aims of treatment are to preserve patency of the coronary artery, augment blood flow through stenotic lesions, […]

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Metronomic Chemotherapy

Metronomic Chemotherapy-1

Guido Bocci • Giulio Francia Editors 2014 Pharmacology and Clinical Applications Metronomic chemotherapy has arrived. In 2014 we are beginning to learn of phase III clinical trial results on this form of cancer treatment, defined by the continuous low-dose administration of conventional chemotherapy drugs. The emerging clinical data will be of paramount importance in allowing […]

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