Modelling the Short QT Syndrome Gene Mutations

Modelling the Short QT Syndrome Gene Mutations-1

Ismail Adeniran 2014 And Their Role in Cardiac Arrhythmogenesis The recently identified genetic short QT syndrome is characterised by abbreviated QT intervals on the electrocardiogram, an increased risk of atrial and ventricular arrhythmias, and an increased risk of sudden death. Although the short QT syndrome has been suggested to provide a paradigm for increasing understanding […]

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Adult and Pluripotent Stem Cells

Adult and Pluripotent Stem Cells-1

Jürgen Hescheler · Erhard Hofer Editors 2014 Potential for Regenerative Medicine of the Cardiovascular System There is hardly an area of research developing so quickly and raising so much hopes and promises as stem cell research. Embryonic, fetal, and adult stem cells provide cells with pluri- and multipotency, respectively, and allow deeper insights into mechanisms […]

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Perinatal Stem Cells

Perinatal Stem Cells-1

Anthony Atala Editor 2014 There has been increasing awareness and interest in the field of stem cell research from researchers, industry, and the general public. This is because of the remarkable potential of stem cells to develop into the many different cell types that are present in the body, providing a cell source for replacement […]

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Perinatal and Prenatal Disorders

Perinatal and Prenatal Disorders-1

Phyllis A. Dennery • Giuseppe Buonocore Ola Didrik Saugstad Editors 2014 The embryonic and fetal period is wrought with oxidative challenges, which can impact development (Chap. 1 ). These lead to long-lasting consequences in neonatal life and beyond. This book will evaluate the continuum of perinatal to postnatal oxidative stress and address possible therapeutic strategies […]

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Mutant p53 and MDM2 in Cancer

Mutant p53 and MDM2 in Cancer-1

Swati Palit Deb • Sumitra Deb Editors 2014 Since its discovery, p53 research has been the highlight of understanding the crucial role of oncogenes and tumor suppressors in regulated or deregulated cell growth. In the last decade, special attention was focused on gain of function mutations of p53 that can turn the tumor suppressor to […]

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Studies on Respiratory Disorders

Studies on Respiratory Disorders-1

Nirmal K. Ganguly • Surinder K. Jindal Shyam Biswal • Peter J. Barnes Ruby Pawankar Editors 2014 Oxygen species constitute an important vehicle of damage in disease pathogenesis including several respiratory diseases. Although the information has been available for more than four decades, it had been difficult to attribute a specific role to oxidative stress in a cause-and-effect […]

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Cellular and Molecular Control of Neuronal Migration

Cellular and Molecular Control of Neuronal Migration-1

Laurent Nguyen • Simon Hippenmeyer Editors 2014 The brain is the most intricate and fascinating organ of our body and its development requires the rigorous control of a multitude of molecular signaling and cellular events. Cell migration is one of these events and represents a fundamental cornerstone of brain development, and homeostasis in the mature brain. The project of […]

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