The Neurochemical Basis of Autism

The Neurochemical Basis of Autism-1

Gene J. Blatt Editor 2010 From Molecules to Minicolumns With the recently perceived increase in incidence of autism and the realization that “autism” may actually be “autisms” with subsets of affected individuals, researchers have been pursuing the possibility that there may be multiple etiologies for the disorder. Although most autism studies have focused on genetics and advanced […]

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The Dopamine Receptors

The Dopamine Receptors-1

Kim A. Neve Editor 2010 As sites of action for drugs used to treat schizophrenia and Parkinson’s disease, dopamine receptors are among the most validated drug targets for neuropsychiatric disorders. Dopamine receptors are also drug targets or potential targets for other disorders such as substance abuse, depression, Tourette’s syndrome, and attention deficit hyperactivity disorder.

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The Aging Auditory System

The Aging Auditory System-1

Sandra Gordon-Salant ● Robert D. Frisina Arthur N. Popper ● Richard R. Fay 2010 Age-related hearing loss (ARHL) is one of the top three most common chronic health conditions affecting individuals aged 65 years and older. The high prevalence of age-related hearing loss compels audiologists, otolaryngologists, and auditory neuroscientists alike to understand the neural, genetic, and molecular mechanisms underlying […]

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Suppressing the Mind

Suppressing the Mind-1

Anthony Hudetz · Robert Pearce Editors 2010 Anesthetic Modulation of Memory and Consciousness Anesthetics produce a reversible state of unconsciousness accompanied by anterograde amnesia. This remarkable phenomenon brings great relief to surgical patients and wonder to clinicians and scientists. To date, we do not fully understand the mechanisms by which anesthetics ablate conscious sensation and memory. We are, however, […]

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Pediatric Neuro-Ophthalmology

Pediatric Neuro-Ophthalmology-1

Michael C. Brodsky 2010 Due to the generous representation of the afferent visual system within the brain, neurological disease may disrupt vision as a presenting symptom or as a secondary effect of the disease. Conversely, early developmental disturbances of vision often disrupt ocular motor control systems, giving rise to complex disorders such as nystagmus, strabismus, and torticollis.

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Neuropsychiatric Disorders

Neuropsychiatric Disorders-1

Koho Miyoshi ● Yasushi Morimura Kiyoshi Maeda Editors 2010 Neuropsychiatry is an integrating neuroscience of neurology and psychiatry that aims to investigate the psychiatric symptoms of neurological disorders as well as the neurobiological bases of psychiatric disorders, including organic mental disorders and endogenous psychoses.

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Neurodegenerative Diseases

Neurodegenerative Diseases-1

Volume Editor: Celia Dominguez 2010 Topics in Medicinal Chemistry 6 The attrition rate in the clinical development of new chemical entities (NCEs) has increased over time, in spite of escalating funds allocated to research and development. Less than 10% of all NCEs succeed in effectively treating some clinical symptom. NCEs develop to treat central nervous system (CNS) disorders, together with […]

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