Edited by SAMIR N. KHLEIF 2005 It all started with an observation. Edward Jenner, an English physician, observed that milkmaids who contracted cowpox were rarely victims of smallpox epidemic, a disease that inflicted a heavy toll on humankind with an estimate of 500 million victims worldwide.

Edited by WILLIAM J. LAROCHELLE RICHARD A. SHIMKETS 2005 Recent advances in genomic and proteomic research into the molecular biology and biochemistry of cancer have revealed critical differences between normal and malignant tissues. Exploiting these differences, investigators from academia as well as the biotechnology and pharmaceutical industries have underscored key processes that regulate the growth and progression of cancers.

M. Kaminishi, K. Takubo, K.Mafune (Eds.) 2005 Pathogenesis, Diagnosis, and Therapy Gastric cancer is still the second leading cause of cancer death worldwide, although the incidence of this disease has been gradually decreasing.Vigorous research on the mechanisms of gastric cancer development, invasion, and metastasis is required to establish prevention, early detection, and precise therapies for gastric cancer.

John Beynon Nicholas D. Carr Editors 2005 In a previous publication, the authors attempted to cover not only topical issues but also difficult problems that might confront recently appointed trainees in the decisions they make that confront these individuals in their future practices.