Confronting Emerging Zoonoses

Confronting Emerging Zoonoses-1

Akio Yamada • Laura H. Kahn • Bruce Kaplan Thomas P. Monath • Jack Woodall • Lisa Conti Editors 2014 The One Health Paradigm According to the United Nations, the global population is estimated to reach 8.1 billion in 2025 and increase to 9.6 billion in 2050. In developing countries, the population is projected to increase to […]

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Bacterial Activation of Type I Interferons

Bacterial Activation of Type I Interferons-1

Dane Parker Editor 2014 Type I interferon (IFN) signaling has long been recognized as a critical component of innate immune defense to viral pathogens. It is now established that bacteria too are able to activate this pathway. Typically bacteria activate type I IFN signaling through TLR-dependent mechanisms, through recognition of LPS in Gram negative organisms or via TLRs and […]

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Antibiofilm Agents

Antibiofilm Agents-1

Kendra P. Rumbaugh • Iqbal Ahmad Editors 2014 From Diagnosis to Treatment and Prevention Volume 8 The editors would like to dedicate this text to the late Dr. Bill Costerton, who is regarded as “The Father of Biofilm.” Bill spent the good part of his career working tirelessly to alert and convince the medical community about the […]

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Molecular Mechanisms in Legionella Pathogenesis

Molecular Mechanisms in Legionella Pathogenesis-1

Hubert Hilbi Editor 2013 Legionnaires’ disease is a potentially fatal pneumonia primarily affecting elderly and immunocompromised persons. The disease is caused by the ubiquitous environmental bacterium Legionella pneumophila, which was first identified more than 35 years ago in the aftermath of a pneumonia epidemic that swept through a convent of the American Legion in Philadelphia, USA. The water-borne bacteria are […]

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