Toxins and Hemostasis

Toxins and Hemostasis-1

R. Manjunatha Kini · Kenneth J. Clemetson · Francis S. Markland · Mary Ann McLane · Takashi Morita Editors 2011 From Bench to Bedside Nature is wonderful; organisms, whether plants, animals or microbes, have evolved through competition (including predator-prey and host-parasite competitions) and natural selection. In this long drawn out process, they have developed, been fine-tuned and improvised […]

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Heart Rate and Rhythm

Heart Rate and Rhythm-1

Onkar N. Tripathi l Ursula Ravens l Michael C. Sanguinetti Editors 2011 Molecular Basis, Pharmacological Modulation and Clinical Implications The heart is a remarkable electrically activated rhythmic muscular pump responsible for distributing blood to the lungs, brain visceral organs, skeletal muscle other organs and to itself.

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Signposts to Chiral Drugs

Signposts to Chiral Drugs-1

Vitomir S ˇ unjic´ l Michael J. Parnham 2011 Organic Synthesis in Action Describing the intrinsic attraction of basic research in organic synthesis, Elias J. Corey, Nobel Laureate in 1990, wrote in 1988: “The appeal of a problem in synthesis and its attractiveness can be expected to reach a level out of all proportion to practical considerations, whenever […]

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Osteoimmunopathology

Osteoimmunopathology-1

Francesco Chiappelli 2011 Evidence-Based Perspectives from Molecular Biology to Systems Biology The U.S. Patient Protection and Affordable Care Act (enacted on 23 March 2010) created a $1 billion program to award, on a competitive basis, federal subsidies to qualifying therapeutic discovery projects being conducted at small biomedical companies.

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Multi-System Endocrine Disruption

Multi-System Endocrine Disruption-1

Jean-Pierre Bourguignon l Bernard Je´gou l Bernard Kerdelhue´ l Jorma Toppari l Yves Christen Editors 2011 In the field of endocrine disruption, the reproductive system has been a priority concern of scientists and environment/public health agencies for several decades, based on observations of fertility impairment in wildlife as well as in humans.

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Methylxanthines

Methylxanthines-1

Bertil B. Fredholm Editor 2011 Methylxanthines are doubtless the most widely consumed of all pharmacologically active agents. The reason for this is, of course, that caffeine-containing beverages are consumed on a daily basis by the majority of humans. The human use of coffee and tea was limited until surprisingly recently.

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