Sphingosine-1-Phosphate Signaling in Immunology and Infectious Diseases

Sphingosine-1-Phosphate Signaling in Immunology and Infectious Diseases-1

Michael B. A. Oldstone • Hugh Rosen Editors 2014 For convenience, the early immune response occurring during the first few days after exposure to a foreign agent is termed innate, while the later response, after day 5, is termed adoptive. Both immune responses have defined cellular components although they vary according to different types of cells and the […]

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Proteins and Proteomics of Leishmania and Trypanosoma

Proteins and Proteomics of Leishmania and Trypanosoma-1

André L.S. Santos • Marta H. Branquinha Claudia M. d’Avila-Levy • Lucimar F. Kneipp Cátia L. Sodré Editors 2014 The so-called neglected tropical diseases comprise a group of infections that is especially endemic in low-income population in developing countries of Africa, Asia and the Americas. In this group, the American ( Trypanosoma cruzi ) and African (Trypanosoma brucei […]

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Neglected Tropical Diseases – Middle East and North Africa

Neglected Tropical Diseases - Middle East and North Africa-1

Mary Ann McDowell • Sima Rafati Editors 2014 The Neglected Tropical Diseases (NTDs) are a group of 17 viral, bacterial, protozoan, and helminth infections that disproportionately affect the most vulnerable populations. The concept of NTDs begun to take shape following the 2000 Millennium Development Goals put forth by the United Nations, specifically Goal # 6 to combat HIV/AIDs, malaria, […]

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How Helminths Alter Immunity to Infection

How Helminths Alter Immunity to Infection-1

William Horsnell Editor 2014 Helminth infections occur globally and all individuals are at some point in their life likely to be exposed to these parasites. Humans have always hosted parasitic worm infections and there is clear evidence that number of important helminth parasites have co-evolved with us. As such helminth infections should be considered a metazoan faunal complement to […]

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Cryptosporidium: parasite and disease

Cryptosporidium

Simone M. Caccio` • Giovanni Widmer Editors 2014 It is more than a 100 years since Cryptosporidium parasites were first described by Edward Tyzzer.1 In addition to the initial discovery, two events stand out for having significantly impacted our awareness of these parasites and the diseases they cause. The HIV epidemic and the emergence of cryptosporidiosis as a […]

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Confronting Emerging Zoonoses

Confronting Emerging Zoonoses-1

Akio Yamada • Laura H. Kahn • Bruce Kaplan Thomas P. Monath • Jack Woodall • Lisa Conti Editors 2014 The One Health Paradigm According to the United Nations, the global population is estimated to reach 8.1 billion in 2025 and increase to 9.6 billion in 2050. In developing countries, the population is projected to increase to […]

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Cancers in People with HIV and AIDS

Cancers in People with HIV and AIDS-1

Robert Yarchoan Editor 2014 Progress and Challenges The field of HIV-associated cancer has undergone a number of changes and advances in the past several years, and this book was conceived to fill the need for a resource that summarizes this new information. The 28 chapters describe the current state of knowledge in this area. These chapters were written […]

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