Edited by Alireza Minagar J. Steven Alexander 2005 Pathogenesis, Immunology, and Clinical Management The last decade witnessed vast scientific advances in our understanding of molecular mechanisms of the inflammatory cascade involved in pathogenesis of diverse neurological disorders. Endothelial cells, activated leukocytes, resident immune cells within the central nervous system (CNS), and many classes of inflammatory mediators, especially chemokines and cytokines, […]

C. Kordon R.-C. Gaillard Y. Christen (Eds.) 2005 Increased awareness over recent years of the role of peripheral hormones in neuronal processes has led to define a ‘humoral brain’ concept. Most lipophilic and some hydrophilic hormones, although not directly involved in cell to cell communication within the brain (with the noticeable exception of neurosteroids, which are synthetized in brain […]

Edited by Irene Litvan 2005 The “atypical parkinsonian disorders,” previously known as “Parkinson plus syndromes,” are characterized by a rapidly evolving parkinsonism that usually has a poor or transient response to dopaminergic therapy and often associates with one or more atypical features. These disorders may be difficult to accurately diagnose, but an early and correct diagnosis is relevant […]

Edited by J.D. Pickard (Editor-in-Chief), N.Akalan, C.Di Rocco V.V. Dolenc, R. Fahlbusch J. Lobo Antunes, M. Sindou N. de Tribolet, C. A. F. Tulleken 2005 As an addition to the European postgraduate training system for young neurosurgeons, we began to publish in 1974 this series of Advances and Technical Standards in Neurosurgery which was later sponsored by […]