MicroRNA in Cancer

MicroRNA in Cancer-1

Suresh Alahari Editor 2013 Cancer is a complex and multistep process involving the accumulation of multiple changes that eventually transform normal cells into cancer cells. These changes include structural and expression abnormalities of both coding and non-coding genes. Most cancer-related deaths are not caused by primary tumors but by the spread of cancer cells from the original site to […]

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Melt Extrusion

Melt Extrusion-1

Michael A. Repka • Nigel Langley James DiNunzio Editors 2013 Materials, Technology and Drug Product Design In the quest to develop new and better therapies to improve the quality of patients’ lives, the pharmaceutical industry has relied on a combination of internal innovation and adaptation of external technologies to progress molecules to medicines. Today, melt extrusion stands as […]

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Machine Learning in Medicine

Machine Learning in Medicine-1

Ton J. Cleophas • Aeilko H. Zwinderman 2013 Part Two Machine learning is a novel discipline concerned with the analysis of large data and multiple variables. It involves computationally intensive methods, is currently mainly the domain of computer scientists, and is already commonly used in social sciences, marketing research, operational research, and applied sciences.

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Long Acting Animal Health Drug Products

Long Acting Animal Health Drug Products-1

Michael J. Rathbone  Arlene McDowell Editors 2013 Fundamentals and Applications Long-acting veterinary formulations play a significant role in animal health, production, and reproduction within the animal health industry. Such technologies offer beneficial advantages to the veterinarian, farmer, and pet owner. These advantages have resulted in long-acting formulations growing in popularity in recent years.

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Lipid-mediated Protein Signaling

Lipid-mediated Protein Signaling-1

Daniel G.S. Capelluto Editor 2013 The intention of this volume is to provide readers with an update on the role of lipids as signaling molecules and how they direct protein signaling to downstream effectors. To understand the specific mechanisms underlying these processes, we recruited renowned scientists who have contributed relevant work in the various areas of lipid signaling research.

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Light Pollution as a New Risk Factor for Human Breast and Prostate Cancers

Light Pollution as a New Risk Factor for Human Breast and Prostate Cancers-1

Abraham Haim • Boris A. Portnov 2013 Humans are diurnal organisms whose biological clock and temporal organization depend on natural light/dark cycles. Throughout evolution, changes in the photoperiod were a signal for seasonal acclimatization of physiological and immune systems as well as of behavioral patterns. The invention of electrical light bulbs created more opportunities for work and leisure.

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Infectious Agents and Cancer

Infectious Agents and Cancer-1

Anton G. Kutikhin • Arseniy E. Yuzhalin Elena B. Brusina 2013 This book is devoted to the role of infectious agents in the etiology of human cancer. Over the years of cancer investigation, a lot of discoveries in this field were made, and many associations between various biological carcinogens and cancer risk were revealed.

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Impact of Genetic Targets on Cancer Therapy

Impact of Genetic Targets on Cancer Therapy-1

Wafik S. El-Deiry Editor 2013 In the last two decades, great strides have been made in unraveling molecular biology, immunology, genetics, and in some cases epigenetics as they apply to the cellular and organ pathology of cancer. This is hugely enabling in many ways as hematologists and oncologists throughout the world strive to develop the best and most personalized […]

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