Mechanism of Muscular Contraction

Mechanism of Muscular Contraction-1

Jack A. Rall 2014 As the title denotes, the purpose of this monograph is to describe the evolution of ideas relating to the mechanism of muscular contraction since the discovery of sliding filaments in 1954. The topic has been approached in its historical development with an emphasis on ideas, techniques, experimental results, and the investigators who generated them.

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Mechanisms of Gene Regulation

Mechanisms of Gene Regulation-1

Carsten Carlberg • Ferdinand Molnár 2014 This textbook describes the fascinating area of eukaryotic gene regulation. Gene expression is shaping the phenotype of cells and tissues; its regulation therefore is the essential fundamental aspect of nearly all processes in physiology, both in health and in disease. For this reason not only biologists and biochemists should be aware of the […]

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Magnetic Resonance and Its Applications

Magnetic Resonance and Its Applications-1

Vladimir I. Chizhik • Yuri S. Chernyshev Alexey V. Donets • Vyacheslav V. Frolov Andrei V. Komolkin • Marina G. Shelyapina 2014 The phenomena that referred to the notion of magnetic resonance are related to quantum radiophysics. Quantum Radiophysics as a branch of science was formed in the beginning of the 1960s. In this field of physics, […]

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Macrophages: Biology and Role in the Pathology of Diseases

Macrophages  Biology and Role in the Pathology of Diseases-1

Subhra K. Biswas • Alberto Mantovani Editors 2014 Macrophages are a key component of the innate immune system and play an essential role in host defense and homeostasis. On the one hand, these cells contribute to host defense by triggering inflammation, displaying microbicidal and tumoricidal properties, regulating the activation of adaptive immunity, resolving inflammation, and promoting tissue repair.  

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Interleukin-10 in Health and Disease

Interleukin-10 in Health and Disease-1

Simon Fillatreau · Anne O’Garra Editors 2014 Responsible Series Editor: Fritz Melchers The maintenance of immune homeostasis, as well as the induction and resolution of immune responses is tightly controlled by the balanced provision of stimulatory and regulatory signals. Interleukin (IL)-10 was identified in 1989, and is the best understood suppressive cytokines of the immune system. The studies […]

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Impact of Energy Balance on Cancer Disparities

Impact of Energy Balance on Cancer Disparities-1

Deborah J. Bowen • Gerald V. Denis • Nathan A. Berger Editors 2014 While great progress has been made across the spectrum of cancer research, extending from prevention, diagnosis, and therapy to survivorship, the benefits of these advances have not been realized by all groups. Significant disparities exist due to a variety of factors including age, gender, ethnicity, […]

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Humanized Mice for HIV Research

Humanized Mice for HIV Research-1

Larisa Y. Poluektova • J. Victor Garcia Yoshio Koyanagi • Markus G. Manz Andrew M. Tager Editors 2014 In 2012, our international editorial team, whose members are listed below, implemented work on a comprehensive textbook, or collection, entitled “Humanized Mice for HIV Research.” In its current completed form, this detailed document is intended to serve as a scientific […]

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Homeostasis – Tumor – Metastasis

Homeostasis - Tumor - Metastasis-1

Gaspar Banfalvi 2014 The understanding of tumor growth is closely related to the basic knowledge of homeostasis, which maintains among several other functions the balance between cell growth and cell death. The first part of the book deals with homeostasis mainly at organismal level, which one could also summarize in one word: health. The loss of growth balance by […]

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