Jeremy C. Wright ● Diane J. Burgess Editors 2012 The evolving complexity of human therapeutics requires the development of novel drug delivery systems. This book encapsulates in a single volume the concepts essential for understanding the science and technology associated with the research and development of long acting injections and implants. It provides a comprehensive overview of the scientific […]

Yoshiharu Takayama 2012 Lactoferrin (lactotransferrin) was first identified as an iron-binding protein abundantly found in milk. It is synthesized by glandular epithelial cells and secreted into body fluids such as saliva, tears and mucosal secretions. Lactoferrin has been considered to play important roles in host defense, since lactoferrin shows broad spectrum of antibacterial and anti-viral activities, arising from its […]

J. Rick Turner 2012 The ultimate purpose of the results from a clinical trial is not to tell us precisely what happened in that trial, but, in combination with results from other trials in the drug’s clinical development program, to gain insight into likely drug responses in patients who would be prescribed the drug should it be approved […]

Stepan S. Batsanov • Andrei S. Batsanov 2012 The subject of structural chemistry is usually defined to include the geometry, i.e. spacial arrangement of atoms, and electronic structure of molecules and crystals. In our opinion, this definition is far too narrow. Firstly, the structures of liquids and amorphous solids are left out or mentioned only briefly.

Selene Baschieri Editor 2012 From Design, Through to Delivery and Testing Prevention of infectious diseases by vaccination is one of the most significant achievements of modern medicine. During the twentieth century, the average human life span in the developed world was about 70 years and it is expected to increase, with a significant portion of this increase directly […]

Andreas Thiel Editor 2012 Progressive alterations in the immune system that develop with aging are encompassed by the terminology “immunosenescence.” These changes have been reported to account for a variety of phenomena leading to a distorted immune competence in the elderly. Immunosenescence covers increased susceptibility to infection and cancer as well as decreased vaccination efficiencies and the altered ability of […]

Jan Schildmann • Verena Sandow Oliver Rauprich • Jochen Vollmann Editors 2012 Ethical, Legal and Socio-Cultural Aspects

Vincenzo Costigliola Editor 2012 New Perspectives Personalised medicine represents an area of increasing importance in the field of health. Both patients and health authorities place great hopes in this new development because it has the potential to provide medical solutions that are far better tailored to the individual patient than the traditional “one-size-fits-all” approach.

 Edited by Monika Fuxreiter, Peter Tompa 2012

Patrizia Agostinis · Afshin Samali (Eds.) 2012 The Endoplasmic Reticulum (ER) is an organelle with extraordinary signaling and homeostatic functions. It is the organelle responsible for protein folding, maturation, quality control, and trafficking of proteins destined for the plasma membrane or for secretion into the extracellular environment.