Shree Ram Singh · Pranela Rameshwar Editors 2014 In recent years, microRNAs (miRNAs) have been emerged as important players in physiological as well as malignant processes. Early research in developmental timing in Caenorhabditis elegans ( C. elegans) led to the discovery of lin-4, the first miRNA gene.

Deborah J. Bowen • Gerald V. Denis • Nathan A. Berger Editors 2014 While great progress has been made across the spectrum of cancer research, extending from prevention, diagnosis, and therapy to survivorship, the benefits of these advances have not been realized by all groups. Significant disparities exist due to a variety of factors including age, gender, ethnicity, […]

Eric C. Schirmer • Jose I. de las Heras Editors 2014 Recent Advances May Elucidate Past Paradoxes It used to be said that “All roads lead to Damascus,” and this was subsequently changed to “Rome.” Today, it might be more appropriate to say “All roads lead to cancer.” Half a century of focused modern research efforts have […]

Edited by Randy Y.C. Poon 2010 Limiting genome replication to once per cell cycle is vital for maintaining genome stability. Although polyploidization is of physiological importance for several specialized cell types, inappropriate polyploidization is believed to promote aneuploidy and transformation. A growing body of evidence indicates that the surveillance mechanisms that prevent polyploidization are frequently perturbed in cancers.

Editedby Jean-Francois Jeannin 2010 Cancer remains a major challenge for modem society. Not only does cancer rank among the first three causes of mortality in most population groups but also the therapeutic options available for most tumor types are limited. The existing ones have limited efficacy, lack specificity and their administration carry major side effects. Hence the urgent need […]

William C.S. Cho Editor 2010 Postgenome science is characterized by omics data related to genome, transcriptome, epigenome, proteome, metabolome and interactome. In the omics era, it is a revolution in cancer research which fundamentally shifts the strategy from piece-bypiece to global analysis and from hypothesis-driven to discovery-based research. This book attempts to take a comprehensive overview on different areas […]

Keshav K. Singh, Leslie C. Costello Editors 2009 We are entering into an era of re-awakening of the importance and interest in the role of altered intermediary metabolism in the development and progression of malignancy. Therefore, this book Mitochondria and Cancer is timely and relevant to contemporary and future research, training, and education. The hallmark studies of Otto Warburg […]

By WOLFGANG ARTHUR SCHULZ 2005 An Advanced Student’s Textbook The present book grew out from a lecture course I have taught for more than 5 years, often together with colleagues who covered topics and cancers they are more familiar with than myself. These lectures were mainly attended by biology and medical students well advanced in their curricula, but […]