Erythropoietins and Erythropoiesis

Erythropoietins and Erythropoiesis-1

Edited by G. Molineux, M.A. Foote, and S.G. Elliott 2006 Molecular, Cellular, Preclinical, and Clinical Biology Research on, and interest in, red blood cell formation spans several centuries and was thought to have peaked in the 1980s with the cloning of the erythropoietin (EPO) gene. In the years subsequent to the cloning of EPO and its expression as […]

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Drugs Affecting Growth of Tumours

Drugs Affecting Growth of Tumours-1

Edited by H.M. Pinedo and C.H. Smorenburg 2006 This volume of the series ‘Milestones’ presents pharmacological, preclinical and clinical data of a wide range of anticancer agents varying from traditional cytotoxic agents to novel targeted small molecules. The chapters have been written by experienced pharmacologists and medical oncologists.  

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Aromatase Inhibitors

Aromatase Inhibitors-1

Edited by B.J.A. Furr 2006 It is over 100 hundred years since the Glaswegian surgeon James Beatson showed that many breast cancers were dependent on the ovaries for their growth. Some time later oestrogen was shown to be the ovarian factor responsible for the development and growth of many breast cancers in both premenopausal and postmenopausal women, in whom […]

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The Vascular Endothelium II

The Vascular Endothelium II-1

Editors Salvador Moncada and Annie Higgs 2006 It was with great pleasure that I accepted the invitation of Springer to edit this book. My association with the vascular endothelium covers a large part of my scientific career and, as with any good long-standing relationship, it has had moments of great excitement and periods of laborious construction. It has sometimes […]

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The Vascular Endothelium I

The Vascular Endothelium I-1

Editors Salvador Moncada and Annie Higgs 2006 It was with great pleasure that I accepted the invitation of Springer to edit this book. My association with the vascular endothelium covers a large part of my scientific career and, as with any good long-standing relationship, it has had moments of great excitement and periods of laborious construction. It has sometimes […]

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Basis and Treatment of Cardiac Arrhythmias

Basis and Treatment of Cardiac Arrhythmias-1

Editors Robert S. Kass and Colleen E. Clancy 2006 In the past decade, major progress has been made in understanding mechanisms of arrhythmias. This progress stems from much-improved experimental, genetic, and computational techniques that have helped to clarify the roles of specific proteins in the cardiac cycle, including ion channels, pumps, exchanger, adaptor proteins, cell-surface receptors, and contractile proteins. […]

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Analgesia

Analgesia-1

Editor Christoph Stein 2007 Analgesics are among the oldest drugs described, albeit not necessarily for medicinal use. For example, the Sumerians isolated opioids (probably for their euphoric effects) in the third millennium b.c. and the use of willow bark (salicin) for fever was first reported in the eighteenth century.  

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The GABA Receptors

The GABA Receptors-1

Edited by S. J. Enna and Hanns Möhler 2007 This volume is the third edition of a monograph series that was first published in 1983. The demand for this work is a testament to the impact of studies on γ-aminobutyric acid (GABA) receptors on the basic understanding of synaptic transmission and on defining the clinical […]

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