Glutamate-based Therapies for Psychiatric Disorders
Phil Skolnick Editor 2010
Continue reading →Category: Pharmacology/Toxicology
New Therapeutic Targets in Rheumatoid Arthritis
Paul-Peter Tak Editor 2009 During the past decades important breakthroughs have been made in the treatment of rheumatoid arthritis (RA). First, the implementation of low-dose methotrexate and other conventional disease-modifying anti-rheumatic drugs was introduced as an effective treatment.
Continue reading →Handbook of Drug Monitoring Methods
Edited by Amitava Dasgupta 2008 Therapeutics and Drugs of Abuse Starting from the 1970s, therapeutic drug monitoring has evolved from monitoring concentrations of a few antiepileptic drugs to a major discipline in today’s laboratory practice. For a drug with a narrow therapeutic range, therapeutic drug monitoring becomes an essential part of patient management, especially because of the development of […]
Continue reading →Drug Testing in Alternate Biological Specimens
Edited by Amanda J. Jenkins 2008 Drug abuse in the developed world is an international problem. In the USA, in an effort to deter drug use and identify abusers so they may receive treatment, testing an individual’s urine has become a large commercial enterprise. Drug testing has also been a traditional part of clinical care in medicine and […]
Continue reading →Bortezomib in the Treatment of Multiple Myeloma
Irene M. Ghobrial, Paul G. Richardson, Kenneth C. Anderson Editors 2011 The proteasome is a highly conserved multicatalytic protease that is responsible for cellular protein turnover, and several therapeutic agents have been developed that specifically target the proteasome. This truly targeted therapy has significantly altered the management of patients with Multiple Myeloma and improved survival.
Continue reading →Basic Principles of Forensic Chemistry
JaVed I. Khan • Thomas J. Kennedy Donnell R. Christian, Jr. 2012 I have not reinvented the wheel on forensic chemistry in this book. This book is merely an effort to consolidate previously developed, yet scattered, forensic chemistry-related information under one umbrella.
Continue reading →Turning up the Heat on Pain: TRPV1 Receptors in Pain and Inflammation
Annika B. Malmberg Keith R. Bley Editors 2005 Despite tremendous advances in the understanding of the sensory nervous system which have accompanied the recent explosive growth of the neurosciences, remarkably few innovative medicines directed towards pain and inflammation are available. Indeed, many patients are still prescribed analgesic and anti-inflammatory medications that were identified long ago as components of herbal […]
Continue reading →Sodium Channels, Pain, and Analgesia
Kevin Coward Mark D. Baker Editors 2005 The treatment of chronic pain, for example that resulting from damage or dysfunction of the nervous system, or that associated with cancer, is at present inadequate and pain still represents a serious unmet clinical need. The costs of pain, in terms of personal anguish, finance and in national healthcare costs are […]
Continue reading →Antibiotics as Anti-Inflammatory and Immunomodulatory Agents
Bruce K. Rubin Jun Tamaoki Editors 2005 The antibiotic era began in earnest during World War II with the “miracle of penicillin”. Following the introduction of penicillin, the quest was on to discover similar antimicrobial agents. In the late 1940s, erythromycin A was isolated from a soil sample found in the Philippine island of Iloilo, and in 1952 […]
Continue reading →Atherosclerosis: Diet and Drugs
Editor Arnold von Eckardstein 2005 Cardiovascular diseases continue to be the leading cause of death in the majority of industrialized countries. The most frequent underlying pathology, namely atherosclerosis, and its clinical sequelae, namely coronary heart disease, cerebrovascular disease and peripheral artery disease, remain common although for a long time we have been made aware of avoidable or modifiable etiological factors […]
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