Editedby Katalin Balogh Attila Patocs 2010 The vast expansion in research on tumorigenesis has greatly increased our understanding of tumor development in patients with inherited endocrine tumor syndromes. This book provides an up-to-date summary from clinical basics and latest follow-up guidelines to the most recent molecular findings in multiple endocrine neoplasia Type I syndrome.
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Edited by Torben Heick Jensen 2010 The diversity of RNAs inside living cells is amazing. We have known of the more “classic” RNA species: mRNA, tRNA, rRNA, snRNA and snoRNA for some time now, but in a steady stream new types of molecules are being described as it is becoming clear that most of the genomic information of […]
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Edited by Gregor Anderluh Jeremy Lakey 2010 Formation of transmembrane pores is a very effective way of killing cells. It is thus not surprising that many bacterial and eukaryotic toxic agents are pore-forming proteins. Pore formation in a target membrane is a complex process composed of several steps; proteins need to attach to the lipid membrane, possibly aggregate […]
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Edited by Nektarios Tavernarakis 2010 Aging is loosely defined as the accumulation of changes in an organism over time. At the cellular level such changes are distinct and multidimensional: DNA replication ceases, cells stop dividing, they become senescent and eventually die. DNA metabolism and chromosomal maintenance, together with protein metabolism are critical in the aging process.
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Edited by A. Graham Pockley M. Gabriella Santoro 2010 All cellular organisms maintain the ability to mount a heat shock response (HSR) when exposed to elevated temperatures. The HSR is a complex cellular response, although its major essence is the induction by heat shock of several cohorts of proteins, heat shock proteins (HSP) in uniquely large concentrations that […]
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Edited by Randy Y.C. Poon 2010 Limiting genome replication to once per cell cycle is vital for maintaining genome stability. Although polyploidization is of physiological importance for several specialized cell types, inappropriate polyploidization is believed to promote aneuploidy and transformation. A growing body of evidence indicates that the surveillance mechanisms that prevent polyploidization are frequently perturbed in cancers.
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Enno Freye 2010 A Comprehensive Review on their Mode of Action, Treatment of Abuse and Intoxication
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William G. Newman Editor 2010
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Karine Clement, Bruce M. Spiegelman Yves Christen Editors 2010 Obesity is a disease of society spreading at an epidemic pace throughout the world. According to the World Health Organization, obesity is defined as an increased or abnormal accumulation of body fat mass to the extent that individual’s health will be negatively affected. Overweight is thus being considered as […]
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Edited by Timothy G. Geary Aaron G. Maule 2010 The need to continually discover new agents for the control or treatment of invertebrate pests and pathogens is undeniable. Agriculture, both animal and plant, succeeds only to the extent that arthropod and helminth consumers, vectors and pathogens can be kept at bay. Humans and their companion animals are also […]
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